ASTM E2180-2007 聚合或疏水材料中掺入抗菌剂的活性测定用标准试验方法

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【英文标准名称】:StandardTestMethodforDeterminingtheActivityofIncorporatedAntimicrobialAgent(s)InPolymericorHydrophobicMaterials
【原文标准名称】:聚合或疏水材料中掺入抗菌剂的活性测定用标准试验方法
【标准号】:ASTME2180-2007
【标准状态】:现行
【国别】:
【发布日期】:2007
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E35.15
【标准类型】:(TestMethod)
【标准水平】:()
【中文主题词】:疏水材料;微生物分析;微生物学;聚合材料;试验方法
【英文主题词】:agarslurry;hydrophobicsurface;percentbacterialreduction;plastics;polymers;quantitativeantibacterialassay
【摘要】:1.1Thistestmethodisdesignedtoevaluate(quantitatively)theantimicrobialeffectivenessofagentsincorporatedorboundintoorontomainlyflat(twodimensional)hydrophobicorpolymericsurfaces.Themethodfocusesprimarilyonassessingantibacterialactivity;however,othermicroorganismssuchasyeastandfungalconidiamaybetestedusingthismethod.1.2Thevehiclefortheinoculumisanagarslurrywhichreducesthesurfacetensionofthesalineinoculumcarrierandallowsformationofa"pseudo-biofilm,"providingmoreevencontactoftheinoculumwiththetestsurface.Note1Thistestmethodfacilitatesthetestingofhydrophobicsurfacesbyutilizingcellsheldinanagarslurrymatrix.Thistestmethod,aswritten,isinappropriatetodetermineefficacyagainstbiofilmcells,whicharedifferentbothgeneticallyandmetabolicallythanplanktoniccellsusedinthistest.1.3Thismethodcanconfirmthepresenceofantimicrobialactivityinplasticsorhydrophobicsurfacesandallowsdeterminationofquantitativedifferencesinantimicrobialactivitybetweenuntreatedplasticsorpolymersandthosewithboundorincorporatedlowwater-solubleantimicrobialagents.Comparisonsbetweenthenumbersofsurvivorsonpreservative-treatedandcontrolhydrophobicsurfacesmayalsobemade.1.4Theprocedurealsopermitsdeterminationof"shelf-life"orlongtermdurabilityofanantimicrobialtreatmentwhichmaybeachievedthroughtestingbothnon-washedandwashedsamplesoveratimespan.1.5Knowledgeofmicrobiologicaltechniquesisrequiredfortheseprocedures.Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.
【中国标准分类号】:G32
【国际标准分类号】:07_100_01
【页数】:3P.;A4
【正文语种】: